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Covid-19 - Treatments & Vaccines

They really need to broaden their recruiting for these trials. It is 89% white for a virus that’s disproportionately impacting Black and Hispanic people albeit for social not biological reasons.
 
They really need to broaden their recruiting for these trials. It is 89% white for a virus that’s disproportionately impacting Black and Hispanic people albeit for social not biological reasons.

They specifically mentioned including more minority participants in the next stage of trials.
 
Covid-19 - Treatments & Vaccines

They specifically mentioned including more minority participants in the next stage of trials.

Right. They need to be doing that in the earliest stages as well. “Looks good for the white people, now let’s try it on everybody else” isn’t sufficient.
 
Right. They need to be doing that in the earliest stages as well. “Looks good for the white people, now let’s try it on everybody else” isn’t sufficient.

Can you tell us why it's not sufficient, using your (undoubtedly vast) personal experience in the different stages of vaccine trials?
 
Can you tell us why it's not sufficient, using your (undoubtedly vast) personal experience in the different stages of vaccine trials?

Seriously? There’s a long history of science and medicine conducting research primarily on white subjects. The risk is that treatments that may be effective on some people will not be effective on others. Clinical trials need to be more diverse.

You can google diversity in clinical trials or any other related search prompt.

District, I’m surprised. That’s something Angus would post. You’re better than this.
 
Seriously? There’s a long history of science and medicine conducting research primarily on white subjects. The risk is that treatments that may be effective on some people will not be effective on others. Clinical trials need to be more diverse.

You can google diversity in clinical trials or any other related search prompt.

District, I’m surprised. That’s something Angus would post. You’re better than this.

Please don't cover up your ignorance with condescending bullshit.

"It is 89% white for a virus that’s disproportionately impacting Black and Hispanic people albeit for social not biological reasons." -PHDeac, 1 day ago.

Drug trials have different phases that focus on different things. Phase 1 is to determine safe dosages, which is affected by a person's biology, not by their social situation.
 
There are enough variations in human biology that it is wise for even phase 1 to capture as wide a swath of that variation as possible early. A for instance, and this is because it is easy, not because it necessarily is relevant in this particular situation, is the sickle cell trait. Sickle cell trait and disease occurs at a much higher rate in populations of African descent than in populations of European descent. If you want to know whether there is any interaction, it is necessary to have a test group of people who are likely to include that.

As human beings, we are all more than 99% alike. But it is that less than 1% variation that makes individuals unique. It would behoove anyone testing drugs and biologics like the Corona virus vaccine to try and capture as broad a swath in that variability as possible, given the limits of size on test groups. Some adverse impacts don't even show until the vaccine goes into widespread use. Test on 50,000 subjects may not show rare impacts that become apparent when the vaccine is administered to 300 million people. That is why the Food and Drug Administration administers the "Adverse Reaction" to drugs and biologics program.

There is a much better chance of finding the adverse events if the test groups are as diverse as possible.
 
people who know things, Fauci talking about a November vaccine

what does that actually mean?
 
people who know things, Fauci talking about a November vaccine

what does that actually mean?

No kidding. Bill Gates, Fauci and a number of other "experts" have also said there will need to be many vaccines, as apparently there are hundreds of mutations (actually one medpress article quoted 6k!) and that one vaccine will hardly protect the masses against the many strains. How many will want to line up to be the first guinea pig to get vaccines when they do come out??? I know many Drs. that would rather not get initial vaccine, but will be required to if they want to continue practicing.

Hope I'm wrong and a vaccine knocks out most strains, but doesn't sound real promising in short-term the way it is mutating. thankfully the new strains are not more deadly, but unfortunately more virulent which could increase deaths ignoring some of the breakthroughs in medicines to treat patients with it.
 
I don't think anything that you just said about strains and mutation rates is correct.

As far as vaccines by November there will most likely be preliminary data from the current trials being run that enroll 30,000 or so people that point to the safety and efficacy at large levels. It changes nothing about when the vaccine will actually be widely available which will be beginning of 2021 at large scale if successful. Now with almost a week or two before the election the notion there is an effective vaccine available be hyped up and the cornavirus problem cured, almost certainly.
 
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