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Thread: Covid-19 - Treatments & Vaccines

  1. #101
    NIAID? Isnít that Fauciís shop? If this is true, Trumpís going to be pissed that he couldnít scream about it being a possible cure on February 22nd.

  2. #102
    Washington Post reports human trials of four vaccine candidates.

    https://www.washingtonpost.com/healt...accine-people/

  3. #103
    Anticoagulants as a treatment?

  4. #104
    Really interesting paper in Science, out today, on managing pandemics under significant uncertainty using multi model decision analysis.

    https://science.sciencemag.org/content/368/6491/577
    Birds are real.

  5. #105
    Quote Originally Posted by WFFaithful View Post
    Anticoagulants as a treatment?
    There is certainly an increase in thrombotic events with COVID. Is there a link to this proposal?

  6. #106
    Quote Originally Posted by Rafi View Post
    There is certainly an increase in thrombotic events with COVID. Is there a link to this proposal?
    https://www.eurekalert.org/pub_relea...-btm050420.php

  7. #107
    Interesting, thanks. This is not a clinical trial, but it's a large study (2700 patients) and they looked at the question of anticoagulants through a number of different approaches (all indicating benefit). A clinical trial of anticoagulants in those with higher inflammatory markers would be really interesting.

  8. #108
    THE quintessential dwarf dartsndeacs's Avatar
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    Covid-19 - Treatments & Vaccines

    I read a story a week or two ago that it was really a million tiny bloodclots that end up in your lungs and obstruct the breathing

    There was also speculation months ago that certain blood types are affected and thatís why the seeming random results of the virus
    just drivin' round in John Voight's car

  9. #109
    Rusty Larue
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    You would think that there would be enough information out there now, based upon the number of cases in the US, to figure out whether blood type matters.

  10. #110
    Quote Originally Posted by DeaconSig View Post
    You would think that there would be enough information out there now, based upon the number of cases in the US, to figure out whether blood type matters.
    It's not very common to know a patient's blood type. That info is only needed if they need a transfusion.

  11. #111
    I donít even know my own blood type.

  12. #112
    Older than Dirt WFU71's Avatar
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    Blood type relationship is discussed here: https://www.livescience.com/why-covi...me-people.html

    "In a more recent study of blood type and COVID-19, published online April 11 to medRxiv, scientists looked at 1,559 people tested for SARS-CoV-2 at New York Presbyterian hospital; of those, 682 tested positive. Individuals with A blood types (A-positive and A-negative) were 33% more likely to test positive than other blood types and both O-negative and O-positive blood types were less likely to test positive than other blood groups. (There's a 95% chance that the increase in risk ranges from 7% to 67% more likely.) Though only 68 individuals with an AB blood type were included, the results showed this group was also less likely than others to test positive for COVID-19."

  13. #113
    Older than Dirt WFU71's Avatar
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    Quote Originally Posted by mako1331 View Post
    I donít even know my own blood type.
    Donate some blood and you'll find out. I'm O negative, so I'm pretty popular with The American Blood Cross.

  14. #114
    Quote Originally Posted by WFU71 View Post
    Donate some blood and you'll find out. I'm O negative, so I'm pretty popular with The American Blood Cross.
    They will have you on a 60 day call cycle.

  15. #115
    Older than Dirt WFU71's Avatar
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    Quote Originally Posted by Deaconblue View Post
    They will have you on a 60 day call cycle.
    They've been calling me every couple of months for many years.

  16. #116
    Here is an article about the Walter Reed Army Institute for Research (WRAIR) and the work they are doing on developing Coronavirus vaccine. Seems like an interesting approach.

    WRAIR vaccine development

  17. #117
    Robert O'Kelley
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    Quote Originally Posted by Deaconblue View Post
    They will have you on a 60 day call cycle.
    I'm O+. I traveled outside the country had to not give for a year. In that time I think they emailed me every couple of days and called a lot. There was no way for me to flag in their system that I was temporarily ineligible. They were relentless.
    Finally was able to donate last week and it's been mercifully quiet.

  18. #118
    ďModerna vaccine shows promising early results in human safety testsĒ. Will be in Stage 3 trials by July.

    Letís hope they have maybe unlocked a key to a cure.

  19. #119
    Quote Originally Posted by DeacsPop View Post
    ďModerna vaccine shows promising early results in human safety testsĒ. Will be in Stage 3 trials by July.

    Letís hope they have maybe unlocked a key to a cure.

    Link to Washington Post article about the Moderna vaccine.

  20. #120
    Looks promising, would need to see neutralizing antibody data because overall making antibodies isn't really the problem. Will be addressed at the proper level during the phase 2 and 3 trials, the problem for those stages is there is no expediting them. To make the correct statistical conclusion of protection those will need to run for months because they aren't going to be direct challenges (No longer possible with ethical considerations) so timescale is still early 2021, though I wouldn't be surprised if things aren't just half-assed for speed.

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