Not sure how easy it is to move up on NET at this stage of the season (still very early), but the ACC only has six teams rated in NET's top 75.
A Quad 1 win is defined as:
#1-30: home
#1-50: neutral
#1-75: away
Wake currently has one quad 1 win. It should go without saying that it is in Wake's best interest for Northwestern to move up to the top 30. They're currently #42.
Unless there is major movement, Wake will only have one (maybe two if UNC moves up from #34 to #30) opportunity to earn a quad 1 win at home during conference play.
Virginia Tech away is a Quad 1 win and that won't change all year.