KU and HUGE Danny Manning fan here-
Talent-wise, you guys are quite a bit better from what I've seen. If he didn't have to recruit, Bruce Almighty would be one of the better coaches in the NCAA in my opinion...good basketball guy and they are a very good defensive team despite his recruiting woes.
Johnson is EASY to get in foul trouble, and while his backup Isaiah Maurice has really improved, he hasn't improved to the point where he's ready to go toe-to-toe with a "Manning-trained" NBA Lottery pick. If you get both of those guys in foul trouble, then the game is OVER. Dean Wade is 6'10" and I have a soft spot for him being a local kid, but he's not looking to bang around with Collins and floats around the perimeter too much offensively. He can get hot though and I'm not sure how good your 4's and 5's are at guarding a stretch 4.
But it's going to come down to how well Stokes, Brown, and Iwundu play. Iwundu is a pro in my opinion and is just a solid all around player with experience. Stokes is emerging to be a pretty solid point guard and Brown at times can be really good but is a streaky shooter. All 3 of those guards really defend though and that's the reason that KSU is even in this position. They are the type of team that can hold a team like West Virginia to 51 points when they are focused.
For you guys, I think you just do what you do, play inside-out to force foul trouble and then they'll have to start doubling which will lead to open 3's. You will get open 3's against them which is good and bad...you'll not want to have a cold-shooting night against them from 3 or that could be your demise.
I have picked Wake in my bracket simply due to the fact that you have better basketball players. I think in the coming years Coach Manning will get your team to buy-in defensively and I think that will get the program back to where it once was. Good luck!