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Bullshit Fox News Says

bym051d said:
The story I read said it lowers the ph of cells and makes them inhospitable to the virus.
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This is probably what they hope for to claim it’s this miracle drug but in reality the mechanism of action is probably more immune modulatory over anything else. There’s a reason why it’s been used for years in autoimmune patients like those with lupus. The patients that anecdotal improve probably would do so using any number of immune suppressive drugs. The reason why it’s inconclusive with trials is because the people it’s helping probably were progressing to a stage of infection where the damage to lungs was no longer the virus but the person own response doing the most damage. Use of chloroquine is going to result in reduce B cell and Tfh cell response, followed by reduced cytokines and further reduction in neutrophil and macrophage infiltrates. The problem with immune modulators is give them too early you make things way worse, give them too late they don’t work at all, and most people’s immune response will work on its own, self regulating. So there’s no actually criteria for prescribing.
 
Colonel Angus said:
It's no secret as I've mentioned it before.

The technical term is "Community organizer".
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You realize it's impossible to have an actual conversation with you, right? What do you get out of this board, man?
 
Louis Gossett Jr said:
This is probably what they hope for to claim it’s this miracle drug but in reality the mechanism of action is probably more immune modulatory over anything else. There’s a reason why it’s been used for years in autoimmune patients like those with lupus. The patients that anecdotal improve probably would do so using any number of immune suppressive drugs. The reason why it’s inconclusive with trials is because the people it’s helping probably were progressing to a stage of infection where the damage to lungs was no longer the virus but the person own response doing the most damage. Use of chloroquine is going to result in reduce B cell and Tfh cell response, followed by reduced cytokines and further reduction in neutrophil and macrophage infiltrates. The problem with immune modulators is give them too early you make things way worse, give them too late they don’t work at all, and most people’s immune response will work on its own, self regulating. So there’s no actually criteria for prescribing.
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So in others words, it's barely above placebo levels, really?
 
Colonel Angus said:
Hmmm - Interesting answer.

So you are a M.D., correct?
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Lol



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Louis Gossett Jr said:
This is probably what they hope for to claim it’s this miracle drug but in reality the mechanism of action is probably more immune modulatory over anything else. There’s a reason why it’s been used for years in autoimmune patients like those with lupus. The patients that anecdotal improve probably would do so using any number of immune suppressive drugs. The reason why it’s inconclusive with trials is because the people it’s helping probably were progressing to a stage of infection where the damage to lungs was no longer the virus but the person own response doing the most damage. Use of chloroquine is going to result in reduce B cell and Tfh cell response, followed by reduced cytokines and further reduction in neutrophil and macrophage infiltrates. The problem with immune modulators is give them too early you make things way worse, give them too late they don’t work at all, and most people’s immune response will work on its own, self regulating. So there’s no actually criteria for prescribing.
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The immunosuppressive effects of hydroxychloroquine take weeks to months, so that’s not the mechanism of action most are proposing. Most are suggesting it prevents cell entry, perhaps by changing the pH.
 
ConnorEl said:
Lol
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Still not an answer. Why do you keep dodging the question?

I'm far from an expert in the field, but my understanding is a "medical doctor" isn't necessarily (or automatically) a M.D.

Feel free to correct if I'm wrong but just trying to get a better understanding of your background/credentials.
 
An osteopath doesn't have a M.D.

So is an osteopath not a medical doctor?
 
Correct.


They are Doctors of Osteopathy.


They may be licensed physicians. Often very good ones.



None of this really matters here, imo. I don’t think appeals to authority are very persuasive, generally.


If you want to share an opinion or make an argument, try and do it on its merits.
 
Brad drilling deep into someone else’s background/credentials, yet when someone asks him his occupation all he offers is an Obama joke.

Interesting.
 
Truly baffling.

Are you going to offer why you think he’s full of shit? Or are you just going to bowrofl?
 
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