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Non-Political Coronavirus Thread

I think most people are testing at home of they have symptoms. Very few are randomly testing without any symptoms, although I guess that depends on your definition of symptoms.

I’ve heard many people that test prior to traveling to visit family. Or for countries/venues that require testing.
 
had a weird sequence of events where my daughter’s private elementary school didn’t make masks mandatory despite our county making it mandatory, then a mom leaked the news to the press and the press forced our school to make masks mandatory
 
So…are you unhappy with the school for initially not following the county? Or for caving?

Or unhappy with the leaking mom and press?
 
had a weird sequence of events where my daughter’s private elementary school didn’t make masks mandatory despite our county making it mandatory, then a mom leaked the news to the press and the press forced our school to make masks mandatory

Snitches get stitches.
 
So…are you unhappy with the school for initially not following the county? Or for caving?

Or unhappy with the leaking mom and press?
unhappy with the school
not making masks mandatory is silly
 
Ohio State announces vaccine requirement for all students, faculty, and staff

https://news.osu.edu/ohio-state-announces-vaccination-requirement/

They're certainly going to have to put in the same game attendance policy that LSU did, one would think. Can't mandate all 80,000 people at the university to get it but then allow 100,000 people on campus/in the stadium on Saturdays with no requirements. This is going to become standard for all schools in reasonably-minded states (surprising that LA is one of those) very soon, methinks.
 
They're certainly going to have to put in the same game attendance policy that LSU did, one would think. Can't mandate all 80,000 people at the university to get it but then allow 100,000 people on campus/in the stadium on Saturdays with no requirements. This is going to become standard for all schools in reasonably-minded states (surprising that LA is one of those) very soon, methinks.

really hard to fathom this, but LSU is currently industry-leading
 
Louisiana has a Democratic governor which gives the school a lot of cover. That's not the case in the rest of the SEC. Republicans hold the House and Senate, which gives them the opportunity to yell and scream about it in order to pander to their base. But they're probably vaccinated so they'll show up for the games (with a PCR test).
 
i suspect as with most SEC tests, plenty of people will be failing and cheating
 
Ohio State announces vaccine requirement for all students, faculty, and staff

https://news.osu.edu/ohio-state-announces-vaccination-requirement/
If you read the fine print, the policy doesn't have quite the teeth the boldface headline would lead you to believe:

..........................................................
What if I do not get either a COVID-19 vaccine or exemption by the October 15, 2021, deadline?

If an individual does not either receive their first dose of vaccine or approval of an exemption by the Friday, October 15 deadline, the individual may be subject to progressive disciplinary action including:

For students:

·       Starting in Spring 2022, existing students will be ineligible to participate in on-campus experiences, including in-person classes or living in the residence halls. 

·       Students who intend to enroll for the first time in spring 2022 will be subject to the same vaccination requirements to participate in in-person classes, live in university residence halls or otherwise take part in on-campus experiences

For faculty and staff:

·       After being reminded of compliance needs, as well as being given time to get into compliance, removal of electronic resources (e.g., logging into their computer, email access)

·       Further progressive discipline
 
Nice vaccine safety paper published in the NEJM. https://www.nejm.org/doi/full/10.1056/NEJMoa2110475

Could be useful if there are some still persuadable people out there who were concerned about possible side effects from the vaccine. 2.4 million people vaccinated, so a massive study to those worried about sample size issues. Bottom line is that serious adverse events with the vaccines are incredibly rare, and those events (along with lots of other bad shit that vaccines don't cause) are much common if you actually get Covid. This figure sums it up.

nejmoa2110475_f4.jpeg
 
Nice vaccine safety paper published in the NEJM. https://www.nejm.org/doi/full/10.1056/NEJMoa2110475

Could be useful if there are some still persuadable people out there who were concerned about possible side effects from the vaccine. 2.4 million people vaccinated, so a massive study to those worried about sample size issues. Bottom line is that serious adverse events with the vaccines are incredibly rare, and those events (along with lots of other bad shit that vaccines don't cause) are much common if you actually get Covid. This figure sums it up.

nejmoa2110475_f4.jpeg

Lymphadenopathy is a term that refers to the swelling of lymph nodes. Lymph nodes are small glands that are responsible for filtering fluid from the lymphatic system.

You're welcome.
 
This is another study that does a good job of showing what’s happening with “waning immunity”.
https://www.biorxiv.org/content/10.1101/2021.08.23.457229v1

Essentially after vaccination you are protected by a high level of circulating antibodies, like most levels of circulation these begin to contract overtime since if they didn’t your blood would just be a goopy mess. The high level prevents actual infection, virus appears and is immediately eliminated before it can get a foothold.

With the change to the delta variant the virus now does a better job of getting a foothold, be it high initial viral loads, and ability to stick, and enter cells. This means you need higher level of circulating antibodies to prevent a foothold, bad when things contract. However with that said you are still prevented from severe disease, hospitalization and death for what will be most likely your lifetime by memory B and T cells.

The memory B and T cells are still rising after 6 months to extremely high levels meaning that if you are exposed to the virus you will pump out antibodies again within days. That’s how you are protected from the bad outcomes but not necessarily cold like symptoms etc… The idea of the third shot is to boost the circulating antibodies to a level that once again is protective from ever getting infected. Anyone that tells you that you will need another booster, etc… has no idea because every vaccine is different when it comes to how long protection will last. Also the spacing of the initial vaccine was probably wrong where it provided higher protection for a shorter period of time instead of less initial protection and more longevity.

This is especially true because the paper shows that the response is not homologous but has a ton of variability between individuals. One person may be protected for a long time, others much less so, we know certain groups this is especially so like the elderly.

F1.large.jpg
 
This is another study that does a good job of showing what’s happening with “waning immunity”.
https://www.biorxiv.org/content/10.1101/2021.08.23.457229v1

Essentially after vaccination you are protected by a high level of circulating antibodies, like most levels of circulation these begin to contract overtime since if they didn’t your blood would just be a goopy mess. The high level prevents actual infection, virus appears and is immediately eliminated before it can get a foothold.

With the change to the delta variant the virus now does a better job of getting a foothold, be it high initial viral loads, and ability to stick, and enter cells. This means you need higher level of circulating antibodies to prevent a foothold, bad when things contract. However with that said you are still prevented from severe disease, hospitalization and death for what will be most likely your lifetime by memory B and T cells.

The memory B and T cells are still rising after 6 months to extremely high levels meaning that if you are exposed to the virus you will pump out antibodies again within days. That’s how you are protected from the bad outcomes but not necessarily cold like symptoms etc… The idea of the third shot is to boost the circulating antibodies to a level that once again is protective from ever getting infected. Anyone that tells you that you will need another booster, etc… has no idea because every vaccine is different when it comes to how long protection will last. Also the spacing of the initial vaccine was probably wrong where it provided higher protection for a shorter period of time instead of less initial protection and more longevity.

This is especially true because the paper shows that the response is not homologous but has a ton of variability between individuals. One person may be protected for a long time, others much less so, we know certain groups this is especially so like the elderly.

F1.large.jpg

This is 100% consistent with what we're learning about the Pfizer vaccine.
 
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