Nah, it’s a good comp. App’s winning % against Wake is pretty much identical to Wake’s against UNC/State.
But it's not because the teams don't play regularly. App hasn't beaten Wake in 20 years despite having won 3 of the past 6.
Also, Wake has fared significantly better against NC State and slightly better against UNC-CH in over 100 games each than App has against Wake in 23 games.